Next generation sequencing is a combination of technologies that are revolutionizing the research of genetics. Entire human genomes can be broken down and studied in one day. Compared to the Sanger technique, next generation sequencing is much more efficient. It dives deeper into the genome to display a broader spectrum of mutations and presents a more sensitive readout. This pioneering development opens the door for genetic research to positively affect so many other aspects of our everyday lives.
Oncology:
While cancer research has used gene sequencing before, next generation sequencing can amplify cancer research by looking more precisely at the genetics of a cancer patient. It can provide a more direct diagnosis and classification of cancer, thus producing improved treatment plans tailored specifically to the patient. Great advances in drug therapy, mutation research, and defense against cancer growth could be monumental.
Bacteriology
From a microbiology aspect, next generation sequencing is becoming the gold standard in bacteriology. According to the National Center for Biotechnology Information, the implementation of next generation sequencing can potentially assist in clinical and public health decisions by determining the causative agent of infectious disease and/or the epidemiology and evolution of various infecting pathogens in the hospital or community settings.
Medicine:
Next generation sequencing is at the forefront of future treatment for diseases. This technology could provide answers to complex genetic disorders such as autism, Huntington’s Disease, Fragile X, and many more. This technology could dissect DNA to help someone learn more about what diseases they are susceptible to later in life. Advancements in understanding and treating mental health disorders such as schizophrenia, bipolar disorder, and depression are just one more way next generation sequencing could transform modern medicine.
Conclusion
Next generation sequencing needs to be more accessible. With greater access, it would allow physicians to bring genetic testing to the bedside, allow therapists and psychologists to use sequencing in diagnosing and treating mental health disorders, and make advances in microbiology testing and laboratory research that could change the world.
סטיב קש 